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Aug 4, 2026Trial update

BeOne Medicines registers Phase 1a/1b trial of RAS inhibitor BG-85738 in solid tumors

BeOne Medicines' first-in-human study of oral RAS inhibitor BG-85738 is recruiting patients with RAS-mutated advanced or metastatic solid tumors.

One new trial record for BeOne Medicines this week.

  • BeOne Medicines is recruiting for a Phase 1a/1b study (NCT07746141) of BG-85738, an oral drug designed to block RAS proteins that are hyperactive1, in patients with RAS-mutated advanced or metastatic solid tumors. The study plans to enroll 100 participants, started on 2026-09-02, and will test BG-85738 alone and in combination with tislelizumab or in combination with cetuximab1, with estimated primary completion on 2028-09-30.

Written by readthrough’s AI from the linked primary sources and fact-checked against them automatically before publishing. Not investment advice.