CardioVision registers heart-failure pathway trial; unrelated ACP and Pilates studies also post

This week's registry updates cover one industry-sponsored cardiology trial and two academic studies unrelated to any single company.

• CardioVision International Tech registered "TORCH-LATAM-004," a stepped-wedge cluster randomized trial of a regional advanced-therapy pathway for adults with advanced heart failure secondary to acquired or structural heart disease who may require heart or combined transplantation, mechanical circulatory or extracorporeal support, advanced structural intervention, or another regulated advanced-therapy pathway.¹ The trial is not yet recruiting, with an estimated enrollment of 360 participants and a primary outcome of completion of the prespecified multidisciplinary evaluation and documentation of an advanced-pathway decision within 90 days after enrollment.¹
• Tufts Medical Center is sponsoring "AEGIS," a trial of an ACP Counselor Video Program aimed at older adults with Alzheimer's Disease and Related Dementias or elevated mortality risk, run with the National Institute on Aging and several academic collaborators. The study is not yet recruiting and plans to enroll an estimated 12174 participants², assessing the impact of the ACP Counselor Video Program on ACP documentation and receipt of goal-concordant care in a diverse sample of older adults with ADRD or other serious illness.²
• Universidade Estadual do Norte do Parana completed a randomized crossover trial on the acute effect of Pilates on blood pressure in women aged 50 and older, enrolling 15 participants. The study compared the acute effect of a Pilates exercise session on blood pressure in women aged 50 years or older against a treadmill walking session.³