Chung Shan Medical University registers trial on slow-paced breathing in heart failure patients

This week's item covers a single newly registered study from an academic sponsor.

• "Effects of Slow-paced Breathing on Heart Rate Variability in Patients With Heart Failure" (NCT07763353), sponsored by Chung Shan Medical University, is listed as not yet recruiting with an estimated start date of 2026-08-15. The trial is a parallel randomized controlled trial in which hospitalized heart failure patients will be assigned to either a slow-paced breathing intervention group or a control group, with both groups receiving standard Phase I cardiac rehabilitation and the intervention group also receiving slow-paced breathing training.¹ The primary outcomes are changes in heart rate variability parameters, including time-domain indices such as SDNN and RMSSD and frequency-domain indices including LF, HF, and LF/HF ratio, measured before and after the intervention.¹ Estimated primary completion is 2027-08-14.