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Nov 4, 2026Trial update

Cidara/Merck Phase 1 trial tests MK-1406 with Fluzone HD vaccine, recruiting

A Phase 1 trial sponsored by Cidara Therapeutics, a Merck & Co. subsidiary, is recruiting to study MK-1406 given alongside Fluzone High-Dose flu vaccine.

One update this week concerns a single Phase 1 trial from Cidara Therapeutics.

  • This is a Phase 1, randomized trial sponsored by Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc.1 Its status is recruiting, with an actual start date of 2025-11-08 and an estimated primary completion date of 2026-12-31, and it plans to enroll 710 participants (estimated)1 in healthy adults. The trial will evaluate whether MK-1406 (formerly CD388) is safe to take with Fluzone® and whether it affects the immune response to Fluzone®, including safety and tolerability when administered with Fluzone® High-Dose (HD) compared to Fluzone® HD with placebo.1

Written by readthrough’s AI from the linked primary sources and fact-checked against them automatically before publishing. Not investment advice.