J&J's TECNIS DEN00V IOL trial terminated for business reasons; results posted

This week's activity centers on a single closed-out cataract trial from Johnson & Johnson Surgical Vision.

• The trial tested the TECNIS IOL, Model DEN00V in comparison to an aspheric monofocal IOL¹ in patients with cataracts. The study was terminated, with the reason given as a business decision¹, after enrolling 243 participants¹. Primary completion and study completion were both listed as 2023-10-24¹, and results were first posted 2026-08-11¹. Participants were randomized in a 1:1 ratio to receive either the investigational IOL Model DEN00V or Control Model ZCB00/DCB00 in both eyes for the duration of the study¹. The primary outcomes measured included monocular photopic distance-corrected intermediate visual acuity (DCIVA) in logMAR at 66 cm for first eyes¹ at a 6-month time frame.