Two new registry studies posted: obesity-linked heart failure and long-term glaucoma surgery outcome

A Poland-based cardiology clinic and a German university hospital each registered observational studies on ClinicalTrials.gov, one on GLP-1/GIP therapy in heart failure, one on glaucoma surgery outcomes.

Two unrelated observational studies were entered into the ClinicalTrials.gov registry this month, one sponsored by a Polish cardiology center and one by a German university hospital.

GLIDE-HF is a prospective, single-center, observational cohort study of patients with obesity-related heart failure with preserved ejection fraction, using GLP-1/GIP receptor agonist therapy as an observed exposure with serial exercise echocardiographic phenotyping¹, sponsored by Miedziowe Centrum Zdrowia SA. The study is listed as not yet recruiting, with an estimated start date of 2027-01-01, and target enrollment of at least 150 patients, recruited continuously from January 2027¹.
The study is recruiting, with approximately 180 participants planned for enrollment², and its primary outcome measures change in intraocular pressure from pre-operative baseline to a single follow-up visit, taken 4 to 10 years after surgery, compared to baseline IOP from medical records².

Fact check notes

In the sourceThe ab-interno trabeculotomy study is recruiting, with approximately 180 participants planned for enrollment.The narrative summary states ~180 participants, but the structured Design/Enrollment field lists 200 participants (estimated), an internal inconsistency in the source. The entry follows the narrative text, which is technically supported, but the discrepancy with the registry's own enrollment field is worth noting.
Checker's noteThe entry states 'approximately 180 participants' for the glaucoma study, matching the narrative text, but the source's structured Enrollment field lists 200 participants (estimated), creating a minor unresolved discrepancy not flagged in the entry.
Sentence removedThe ab-interno trabeculotomy study is a single-center, observational study with a retrospective pre-operative baseline and a prospective cross-sectional follow-up visit evaluating long-term outcomes of the Trabectome procedure in glaucoma patients, sponsored by Wuerzburg University Hospital (Würzburg, Germany).copied source wording

Written by readthrough’s AI from the linked primary sources and fact-checked against them automatically before publishing. Where the check questioned a sentence, its note is shown above. Not investment advice.