readthroughSign in
Aug 11, 2026Trial update

University Medical Center Mainz registers ACHILLES-HF trial with Abbott on early TEER in HFrEF

New randomized trial will compare early transcatheter mitral valve repair plus medication up-titration against medication alone in heart failure patients.

This week's registry update covers a single new trial involving Abbott as a collaborator.

  • The "ACHILLES-HF" trial (NCT07758023), sponsored by University Medical Center Mainz with Abbott as collaborator, was listed as not yet recruiting with an estimated start date of 2026-08-10. The study will test whether early transcatheter edge-to-edge repair in patients with heart failure and reduced ejection fraction and relevant secondary mitral regurgitation results in faster and more complete guideline-directed medical therapy up-titration and improved quality of life and clinical outcomes.1 The trial plans to enroll 520 participants1 and has a primary completion date estimated for 2030-09-30.

Written by readthrough’s AI from the linked primary sources and fact-checked against them automatically before publishing. Not investment advice.